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I did a few 2-up rides this summer with the wife on the back, with a group of others who had their women-folk on the back as well. I always found myself lagging behind, simply because I'd feel really awful if my wife had to experience the pain of a road-slide because I tried to ride too hard with her on the back.
Seems like most of my riding partners ride pretty hard with a passenger. I assume having a passenger drastically changes the handling characteristics of your bike. Am I just being a huge pussy?